Susan Chaityn Lebovits
Journalist
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Medicine

The multidrug transporter EmrE functions as an asymmetric antiparallel dimer (molecule with two subunits). Drug (blue) transport from the inside to the outside of the cell membrane is accomplished by exchange between inward (left) and outward (right) facing conformations in exchange with two protons (green), directly visualized by nuclear magnetic resonance spectroscopy.

Closer to understanding, averting drug resistance

Impeding exportation of antibiotics from cells while maintaining necessary nutrients crucial

By Susan Chaityn Lebovits | January 30, 2012

Bacterial resistance to antibiotics is growing exponentially, contributing to an estimated 99,000 deaths from hospital-associated infections in the U.S. annually, according to the Centers for Disease Control and Prevention. One reason that this is happening is that drug resistant proteins are transporting “good” antibiotics, or inhibitors, out of the cells, leaving them to mutate. In […]

Posted in Science Articles | Tagged Drugs, Medicine, Science, Technology

Copyright © 2021 Susan Chaityn Lebovits.